High Throughputs

Articles providing an engineering perspective on drug development.

Codon Optimization

Codon optimization is the process of modifying a gene's DNA sequence to use codons preferred by the host organism, without changing the amino acid sequence, to enhance protein expression. By aligning codon usage with the host's tRNA abundance, it improves translation efficiency and increases protein yield.

Kozak Sequences

The Kozak sequence is a specific nucleotide sequence in eukaryotic messenger RNA (mRNA) that plays...

Selecting the right expression vector

Expression vectors are plasmids used to express a gene of interest in a cellular host. Selecting...

Protein Expression Optimization Process

Scientists in charge of protein expression optimization projects all too often fly by the seat of...

Plasmid Certification Using GenoDIN

Track your plasmids and their documentation, control their dissemination, and ensure your plasmids'...

Vero Cells: Green Kidneys to Produce Vaccines

Vero cells are commonly used to study viruses, treatments, and vaccines. The reason for this lies...

HEK293: An Essential Human Cell Line with a Unexpected Origin

HEK 293 cells and their derived cell lines are widely used in research and biotechnology....

Expression Vector Optimization for Protein Production

Most recombinant proteins can be produced by simply cloning the corresponding genes into standard...